What is Polymyalgia Rheumatica?
Polymyalgia rheumatica causes marked pain and stiffness of the shoulder and hip girdles, almost always in people over 50 and typically over 65. Onset is often strikingly abrupt — patients can name the week it began.
It closely overlaps with giant cell arteritis: roughly 15% of PMR patients develop GCA, and about half of GCA patients have PMR symptoms. Every PMR patient is therefore screened for headache and visual symptoms at every visit.
The response to low-dose steroids is usually dramatic, often within 72 hours. A poor response should trigger a serious rethink of the diagnosis rather than a dose increase.
IllustrativeSymptoms of Polymyalgia Rheumatica
Early signs
- Aching and stiffness in both shoulders, upper arms, neck, hips and thighs
- Severe morning stiffness lasting more than 45 minutes
- Difficulty raising the arms to comb hair, or getting out of bed and low chairs
- Fatigue, low-grade fever, poor appetite and weight loss
- Markedly elevated ESR and CRP
If left untreated
- Shoulder capsule inflammation with restricted movement
- Peripheral joint swelling and carpal tunnel syndrome
- Depression and disturbed sleep from unrelieved pain
- Steroid complications when treatment is prolonged without monitoring
- Development of giant cell arteritis features
Causes & risk factors
- Age over 50, with incidence rising steeply with each decade
- Genetic factors including HLA-DRB1*04 associations
- Possible seasonal or infective triggers
- Female sex — roughly twice as common in women
- Underlying large-vessel inflammation demonstrable on PET in many patients
How Polymyalgia Rheumatica is diagnosed
No single test diagnoses a rheumatic disease. The diagnosis comes from combining the pattern of symptoms, the examination findings, and only the investigations that answer a specific question.
Clinical pattern recognition
Age over 50, bilateral shoulder or hip girdle pain, morning stiffness over 45 minutes and raised inflammatory markers form the core of the diagnosis.
ESR and CRP
Usually significantly elevated. A small subset has normal markers, which makes careful exclusion of alternatives even more important.
Systematic exclusion of mimics
Late-onset rheumatoid arthritis, hypothyroidism, statin myopathy, multiple myeloma, malignancy and infection are all actively ruled out — CPK, protein electrophoresis, thyroid function and imaging as needed.
Shoulder and hip ultrasound
Subacromial bursitis, biceps tenosynovitis and hip bursitis support the diagnosis objectively.
Giant cell arteritis screening
Direct questioning about headache, scalp tenderness, jaw claudication and visual symptoms at every single visit — this is what prevents avoidable blindness.
Treatment options
Low-dose prednisolone
Usually 12.5–25 mg daily. A rapid, near-complete response within a week is expected and is itself part of confirming the diagnosis.
Structured, slow taper
Reduction over 12–24 months guided by symptoms and CRP. Tapering too quickly is the commonest cause of relapse and of unnecessarily prolonged total treatment.
Methotrexate as a steroid-sparing agent
Added for relapsing disease, or where diabetes, osteoporosis or glaucoma make steroid exposure especially risky.
Tocilizumab
Considered in refractory PMR and established in GCA, allowing substantially lower cumulative steroid doses.
Mandatory bone and metabolic protection
Calcium, vitamin D, DEXA and a bisphosphonate where indicated, plus blood sugar, blood pressure and eye monitoring from day one of steroids.
Seek urgent medical attention if you have
- New headache, scalp tenderness or jaw pain on chewing — possible giant cell arteritis
- Any visual disturbance, even brief — treat as an emergency
- Poor or absent response to an adequate steroid dose within a week
- Weight loss, night sweats or bone pain suggesting malignancy
- Progressive proximal weakness rather than pain-limited weakness (myositis)
Do not wait for a scheduled appointment for any of the above. Call the clinic on +91 70571 19999 or attend the nearest emergency department.
Frequently asked questions about Polymyalgia Rheumatica
How long will I need steroids?
Is PMR the same as fibromyalgia?
Why do I keep being asked about headaches?
Get an expert opinion on Polymyalgia Rheumatica in Pune
Consultations at the Ravet clinic in Pimpri-Chinchwad. Bring your previous reports — a properly reviewed history usually saves repeating tests.
Part of a wider group
Inflammatory ArthritisJoint swelling that is driven by the immune system, not by wear.Related conditions
Vasculitis
Inflammation of blood vessels — where days of delay can cost sight, kidneys or life.
Rheumatoid Arthritis
Symmetric small-joint swelling that responds best when treated within the first 12 weeks.
Osteoporosis
Silent until the first fracture — which is exactly why it should be screened for, not waited for.